腹板波浪度测量仪在桥式起重机检测中的应用

本文介绍武汉钢铁学院研制的QFP-Ⅱ型起重机腹板波浪度测量仪的结构原理,及其在桥式起重机金属结构性能检测中的使用方法,并根据桥式起重机产品质量分等规定的技术要求,给出腹板波浪度分析计算方法。     

B值随机变量序列部分和的矩的收敛速度

本文讨论2阶一致光滑空间及2型空间中随机变量序列部分和的矩的收敛速度问题,所得定理推广了Chow的结果。     

矿区铁路专用线下综采放顶煤开采的试验研究

介绍了国内第一个综采放顶煤开采矿区铁路线下压煤试验面的成功经验，总结了试采中对铁路所采取的各种分析和维护措施，分析了该采煤方法下的地在移动和变形特点，为我国“三下”采煤领域提供了具有特色的成功实例。     

高校三标一体管理体系与人本思想

三标一体作为一个完整的、全方位的管理体系富含深刻的人本管理思想,具体而言包括尊重人、关心人、解放人、发展人和依靠人。在“三标一体”管理体系下,高校管理中贯彻以人为本思想必须把握关键。     

Electrochemical studies of glutathione monolayer assembled on a polycrystalline gold electrode

The glutathione (GSH) monolayer and complex monolayer of GSH-metallic ion on polycrystalline gold electrode were studied by using K₃Fe(CN)₆ as the redox probe. As for the GSH monolayer, it was found that the metallic ions could open the ion-gate in the monolayer dramatically in the order La³⁺> Pb²⁺>>Ba²⁺>Ca²⁺ whereas Zn²⁺ ion closed the ion-gate. The complexes of GSH-metallic ions were capable of self-assembling the different kind of monolayer. All the differences were related to the structural configuration of the anchored GSH molecule, which changed with different metallic ions or pH. Biography:Fang Cheng (1971-) male, Ph. D, research direction: electroanlysis.     

技术创新与技校教学浅谈

技术创新具有独特的结构和内含。而职业技校要培养有创新意识的技术工人和技术员，就必须使学生既要掌握理论知识，又要学得生产技能。只有两者有机结合，才能为技术创新打好基础。     

β-桉烯和其衍生物的合成及其抗生育活性

本文叙述了倍半萜类化合物——β-桉烯、衍生物Neointermedeol以及1,2,3,4,7,8-六氢-5,8-二甲基-3-异丙烯基萘的合成。初步药理筛选结果表明,这三个化合物均具有一定的抗生育活性。化合物还未见报道,它的化学结构在本文得到证实。     

钢绳罐道上容器的摆动和晃动

本文研究了钢绳罐道上提升容器的横向运动,它包括容器质心的横向摆动和绕质心的转动。建立了此系统的动力学微分方程组,并用龙格——库塔方法求得了运动的数值解。通过对数值解的分析说明:(1)容器的摆动量与提升钢绳的横向力,以及罐道长度成正比,与重锤的重量成正比。(2)在容器长度确定的条件下,增大上下罐耳之间的距离可使容器的晃动减小。但是,如果容器长度与罐耳间的距离同步地增加,将不能达到使晃动减小的目的。     

高速磁浮曲线地段简支轨道梁墩体系动力响应仿真

应用桥梁动力学、车辆动力学和电磁相互作用原理建立了高速常导磁浮交通车-梁-墩体系动力分析模型,利用数值积分求解了大规模非线性耦合动力方程.在此基础上结合具体线路条件进行了车线耦合动力学检算,得到了曲线地段车辆及梁墩体系动力响应基本规律.该部分的研究为制订合理的高速磁浮线路设计标准提供了理论依据.     

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

The recycling of the amyloid precursor protein (APP) from the cell surface via the endocytic pathways plays a key role in the generation of amyloid beta peptide (Abeta) in Alzheimer disease. We report here that inherited variants in the SORL1 neuronal sorting receptor are associated with late-onset Alzheimer disease. These variants, which occur in at least two different clusters of intronic sequences within the SORL1 gene (also known as LR11 or SORLA) may regulate tissue-specific expression of SORL1. We also show that SORL1 directs trafficking of APP into recycling pathways and that when SORL1 is underexpressed, APP is sorted into Abeta-generating compartments. These data suggest that inherited or acquired changes in SORL1 expression or function are mechanistically involved in causing Alzheimer disease.